anti-FRMD8 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 靶点名称:
- 抗原物种:
- 抗原:
- 偶联标记:
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Brand:
CAT.NO. : ARG67125
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FRMD8 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 靶点名称 | FRMD8 |
| 抗原物种 | Human |
| 抗原 | N-terminal region of human FRMD8 |
| 偶联标记 | Un-conjugated |
| 別名 | FRMD8; FERM Domain Containing 8; ITAP; IRhom Tail-Associated Protein; FKSG44; FERM Domain-Containing Protein 8; Band4.1 Inhibitor LRP Interactor; FLJ90369; Bili |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Potassium phosphate(pH 7.3) with 0.9% Sodium chloride, 30% glycerol, and 0.01% sodium azide |
| 抗菌剂 | 0.01% sodium azide |
| 稳定剂 | 30% glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FRMD8 |
| 全名 | FERM Domain Containing 8 |
| 背景介绍 | Involved in positive regulation of tumor necrosis factor production. Located in several cellular components, including centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface.[Uniprot] |
| 细胞定位 | Cell membrane, Cytoplasm, Membrane |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (1)
ARG67125 anti-FRMD8 antibody WB image
Western blot: K562 stained with ARG67125 anti-FRMD8 antibody.
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