anti-GABAA Receptor alpha 4 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG64825
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes GABAA Receptor alpha 4 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GABAA Receptor alpha 4 |
| 抗原物种 | Human |
| 抗原 | C-EKAKRKTSKPPQE |
| 偶联标记 | Un-conjugated |
| 別名 | A; Gamma-aminobutyric acid receptor subunit alpha-4; GABA |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P48169 Human Gamma-aminobutyric acid receptor subunit alpha-4 |
|---|---|
| 背景介绍 | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 62 kDa |
检测图片 (2)
ARG64825 anti-GABAA Receptor alpha 4 antibody WB image
Western blot: Human Frontal Cortex lysate (35 µg protein in RIPA buffer) stained with ARG64825 anti-GABAA Receptor alpha 4 antibody at 0.1 µg/ml dilution.
ARG64825 anti-GABAA Receptor alpha 4 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Cortex. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64825 anti-GABAA Receptor alpha 4 antibody at 2.5 µg/ml dilution followed by AP-staining.
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