anti-GABAA Receptor beta 1 phospho (Ser434) antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GABAA Receptor beta 1 phospho (Ser434)
  • 反应物种: Hu, Mk
  • 预测物种: Ms, Rat
  • 应用: IHC-P, WB
  • 特异性: This antibody detects endogenous levels of GABAA Rβ1 protein only when phosphorylated at Ser434.
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GABAA Receptor beta 1
  • Brand:
CAT.NO. : ARG66236
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GABAA Receptor beta 1 phospho (Ser434)
反应物种Hu, Mk
预测物种Ms, Rat
应用IHC-P, WB
特异性This antibody detects endogenous levels of GABAA Rβ1 protein only when phosphorylated at Ser434.
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GABAA Receptor beta 1
抗原物种Human
抗原Phosphospecific peptide around Ser434 of Human GABAA Receptor beta 1.
偶联标记Un-conjugated
別名A; Gamma-aminobutyric acid receptor subunit beta-1; GABA
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:300
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量55 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol and 0.5% BSA
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2560 Human GABRB1

Swiss-port # P18505 Human Gamma-aminobutyric acid receptor subunit beta-1

基因名称GABRB1
全名gamma-aminobutyric acid (GABA) A receptor, beta 1
背景介绍The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
生物功能Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity). [UniProt]
预测分子量54 kDa
检测图片 (1)
  • ARG66236 anti-GABAA Receptor beta 1 phospho (Ser434) antibody WB image

    Western blot: COS7 cell lysate stained with ARG66236 anti-GABAA Receptor beta 1 phospho (Ser434) antibody.

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