anti-GALNT7 antibody
CAT.NO. : ARG44582
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GALNT7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GALNT7 |
| 抗原物种 | Human |
| 抗原 | Human GALNT7 recombinant protein (aa. sequence: K67-V657). |
| 偶联标记 | Un-conjugated |
| 別名 | GALNT7; Polypeptide N-Acetylgalactosaminyltransferase 7; Polypeptide GalNAc Transferase 7; GALNAC-T7; UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 7 (GalNAc-T7); UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 7; Protein-UDP Acetylgalactosaminyltransferase 7; N-Acetylgalactosaminyltransferase 7; Pp-GaNTase 7; EC 2.4.1.41; EC 2.4.1.37; GalNAc-T7; GalNAcT7; EC 2.4.1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 抗菌剂 | 4% Trehalose |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GALNT7 |
| 全名 | Polypeptide N-Acetylgalactosaminyltransferase 7 |
| 背景介绍 | This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. [Uniprot] |
| 细胞定位 | Golgi apparatus, Membrane. [Uniprot] |
| 预测分子量 | 75 kDa |
| 翻译后修饰 | Disulfide bond. [Uniprot] |
检测图片 (3)
ARG44582 anti-GALNT7 antibody WB image
Western blot: HeLa, HepG2, A431 and Hacat stained with ARG44582 anti-GALNT7 antibody at 0.5 μg/mL dilution.
ARG44582 anti-GALNT7 antibody WB image
Western blot: Rat brain and Rat kidney stained with ARG44582 anti-GALNT7 antibody at 0.5 μg/mL dilution.
ARG44582 anti-GALNT7 antibody WB image
Western blot: Mouse brain and Mouse kidney stained with ARG44582 anti-GALNT7 antibody at 0.5 μg/mL dilution.
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