anti-GARS antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GARS
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GARS
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human GARS.
  • Brand:
CAT.NO. : ARG57697
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GARS
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GARS
抗原物种Human
抗原Recombinant protein of Human GARS.
偶联标记Un-conjugated
別名DSMAV; HMN5; Glycine--tRNA ligase; Glycyl-tRNA synthetase; SMAD1; CMT2D; EC 6.1.1.14; Diadenosine tetraphosphate synthetase; GlyRS; AP-4-A synthetase
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:1000 - 1:4000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U87
实际分子量~ 83 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2617 Human GARS

GeneID: 353172 Mouse GARS

Swiss-port # P41250 Human Glycine--tRNA ligase

Swiss-port # Q9CZD3 Mouse Glycine--tRNA ligase

基因名称GARS
全名glycyl-tRNA synthetase
背景介绍This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. [provided by RefSeq, Jul 2008]
生物功能Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. [UniProt]
细胞定位Cell projection, Cytoplasm, Mitochondrion, axon. [UniProt]
预测分子量83 kDa
检测图片 (2)
  • ARG57697 anti-GARS antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG57697 anti-GARS antibody at 1:100 dilution.

  • ARG57697 anti-GARS antibody WB image

    Western blot: 25 µg of U87 cell lysate stained with ARG57697 anti-GARS antibody at 1:5000 dilution.

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