anti-Gastrin antibody [SQab30315]

CAT.NO. : ARG67033

US＄ Please choose

Size:

100 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Recombinantrabbit Monoclonal antibody [SQab30315] recognizes Gastrin
反应物种	Hu
应用	IHC-P
宿主	Rabbit
克隆	Monoclonal
克隆号	SQab30315
同位型	IgG
靶点名称	Gastrin
抗原物种	Human
抗原	Synthetic peptide of Human Gastrin.
偶联标记	Un-conjugated
Protein Full name	Gastrin
別名	GAST, Gastrin, GAS, Preprogastrin

应用说明

应用建议

应用	推荐稀释比
IHC-P	1:50 - 1:100

应用说明

The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

阳性对照

Human gastric cancer

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
抗菌剂	0.01% Sodium azide
稳定剂	40% Glycerol and 0.05%BSA
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 2520 Human GAST Swiss-port # P01350 Human Gastrin
基因名称	GAST
全名	Gastrin
背景介绍	Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
生物功能	Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. [Uniprot]
细胞定位	Secreted
预测分子量	16 kDa
翻译后修饰	Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. [Uniprot]

检测图片 (1)

ARG67033 anti-Gastrin antibody [SQab30315] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded human gastric cancer stained with ARG67033 anti-Gastrin antibody [SQab30315].

New Products