anti-GCNT1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GCNT1
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GCNT1
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide corresponding to aa. 88-117 of Human GCNT1.
  • Brand:
CAT.NO. : ARG59635
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GCNT1
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GCNT1
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 88-117 of Human GCNT1.
偶联标记Un-conjugated
別名NAGCT2; Core 2 GNT; G6NT; C2GNT1; Core 2-branching enzyme; Core2-GlcNAc-transferase; NACGT2; C2GNT; EC 2.4.1.102; C2GNT-L; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2650 Human GCNT1

Swiss-port # Q02742 Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminylt

基因名称GCNT1
全名glucosaminyl (N-acetyl) transferase 1, core 2
背景介绍This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
生物功能Glycosyltransferase that catalyzes the transfer of an N-acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O-glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. [UniProt]
细胞定位Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network. [UniProt]
预测分子量50 kDa
检测图片 (1)
  • ARG59635 anti-GCNT1 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cancer tissue stained with ARG59635 anti-GCNT1 antibody.

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