anti-GDNF antibody (Biotin)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes GDNF |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GDNF |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human GDNF. (MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI) |
| 偶联标记 | Biotin |
| 別名 | ATF; Astrocyte-derived trophic factor; HSCR3; hGDNF; Glial cell line-derived neurotrophic factor; HFB1-GDNF; ATF1; ATF2 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # P39905 Human Glial cell line-derived neurotrophic factor |
|---|---|
| 基因名称 | GDNF |
| 全名 | glial cell derived neurotrophic factor |
| 背景介绍 | This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010] |
| 生物功能 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. [UniProt] |
| 预测分子量 | 24 kDa |
ARG56798 anti-GDNF antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human GDNF stained with ARG56798 anti-GDNF antibody (Biotin), under reducing conditions.
ARG56798 anti-GDNF antibody (Biotin) standard curve image
Direct ELISA: ARG56798 anti-GDNF antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
ARG56798 anti-GDNF antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human GDNF stained with ARG56798 anti-GDNF antibody (Biotin), under non-reducing conditions.
ARG56798 anti-GDNF antibody (Biotin) standard curve image
Sandwich ELISA: ARG56798 anti-GDNF antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56689 anti-GDNF antibody as a capture antibody. Results of a typical standard run with optical density.
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