anti-GDNF Receptor alpha 1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GDNF Receptor alpha 1
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 特异性: GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins.
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GDNF Receptor alpha 1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG23602
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GDNF Receptor alpha 1
反应物种Hu
应用IHC-P, WB
特异性GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins.
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GDNF Receptor alpha 1
抗原物种Human
抗原Synthetic peptide around 14 aa (Center) of Human GDNF receptor alpha 1.
偶联标记Un-conjugated
別名GDNFR-alpha-1; GDNFRA; GFR-ALPHA-1; RET ligand 1; GFR-alpha-1; RET1L; GDNF receptor alpha-1; TRNR1; TGF-beta-related neurotrophic factor receptor 1; RETL1; GDNFR; GDNF family receptor alpha-1
应用说明
应用建议
应用推荐稀释比
IHC-P1 µg/ml
WB1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Human Brain
属性
形式Liquid
纯化DEAE purified.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2674 Human GFRA1

Swiss-port # P56159 Human GDNF family receptor alpha-1

基因名称GFRA1
全名GDNF family receptor alpha 1
背景介绍Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]
生物功能Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity). [UniProt]
预测分子量51 kDa
检测图片 (3)
  • ARG23602 anti-GDNF Receptor alpha 1 antibody IHC-P image

    Immunohistochemistry: Human brain tissue stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 1 µg/ml dilution.

  • ARG23602 anti-GDNF Receptor alpha 1 antibody WB image

    Western blot: Crude membrane fractions of Human brain, liver, kidney, and spleen lysates stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 1 µg/ml dilution.

  • ARG23602 anti-GDNF Receptor alpha 1 antibody IHC-P image

    Immunohistochemistry: Human brain tissue stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 2.5 µg/ml dilution.

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