anti-GFAP antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG52313
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Product Details
概述
| 产品描述 | Chicken Polyclonal antibody recognizes Glial Fibrillary Acidic Protein (GFAP) |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Cat, Chk, R. Mk, Rb |
| 应用 | ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Chicken |
| 克隆 | Polyclonal |
| 同位型 | IgY |
| 靶点名称 | GFAP |
| 抗原物种 | Bovine |
| 抗原 | Recombinant and purified bovine GFAP |
| 偶联标记 | Un-conjugated |
| 別名 | Glial fibrillary acidic protein; ALXDRD; GFAP |
应用说明
| 应用建议 |
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| 应用说明 | Specific for the ~50kDa GFAP protein. A lower band at ~45kDa is a proteolytic fragment derived from the GFAP molecule. Astrocytes stain strongly and specifically in a clearly filamentous fashion with this antibody. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Total IgY fraction |
| 缓冲液 | Total IgY fraction in PBS and 10 mM Sodium azide |
| 抗菌剂 | 10 mM Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GFAP |
| 全名 | glial fibrillary acidic protein |
| 背景介绍 | GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| 生物功能 | GFAP is a class-III intermediate filament. It is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. [UniProt] |
| 产品亮点 | Related Antibody Duos and Panels: ARG30324 Neuroinflammation Antibody Panel Related products: GFAP antibodies; GFAP Duos / Panels; Anti-Chicken IgY secondary antibodies; Related news: Stem cell and the regenerative medicine: Ready for the patients Astrocyte-to-neuron conversion for Parkinson's disease treatment |
| 研究领域 | Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody; Astrocyte Marker antibody; Astrocyte Maturation Marker antibody; Neuroinflammation antibody; Brain Injury IHC Study antibody |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Phosphorylated by PKN1. |
检测图片 (2)
ARG52313 anti-GFAP antibody WB image
Western Blot: Rat cortex lysate showing specific immunolabeling of the ~50k GFAP protein stained with ARG52313 anti-GFAP antibody.
ARG52313 anti-GFAP antibody ICC/IF image
Immunofluorescence: Mixed cultures of neurons and glia stained with ARG52313 anti-GFAP antibody (red), and DNA (blue). Astrocytes stain strongly and specifically in a clearly filamentous fashion with this antibody.
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