anti-GFAP antibody [GF-02]

产品描述: Mouse Monoclonal antibody [GF-02] recognizes Glial Fibrillary Acidic Protein (GFAP)
反应物种: Hu, Pig
应用: ICC/IF, IHC-Fr, IHC-P, WB
特异性: The clone GF-02 exclusively reacts with intact GFAP molecules. GFAP is the principal marker of astroglial cells in the central nervous system; it is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene.
宿主: Mouse
克隆: Monoclonal
克隆号: GF-02
同位型: IgM
靶点名称: GFAP

CAT.NO. : ARG62992

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [GF-02] recognizes Glial Fibrillary Acidic Protein (GFAP)
反应物种	Hu, Pig
应用	ICC/IF, IHC-Fr, IHC-P, WB
特异性	The clone GF-02 exclusively reacts with intact GFAP molecules. GFAP is the principal marker of astroglial cells in the central nervous system; it is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves. The GFAP protein runs on gels at ~55 kDa protein, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene.
宿主	Mouse
克隆	Monoclonal
克隆号	GF-02
同位型	IgM
靶点名称	GFAP
抗原物种	Pig
抗原	Pellet of porcine brain cold-stable proteins after depolymerization of microtubules.
偶联标记	Un-conjugated
別名	Glial fibrillary acidic protein; ALXDRD; GFAP

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from ascites by thiophilic adsorption-affinity chromatography and precipitation methods.
纯度	> 95% (by SDS-PAGE)
缓冲液	TBS (pH 8.0) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 2670 Human GFAP GeneID: 396562 Pig GFAP Swiss-port # P14136 Human Glial fibrillary acidic protein
背景介绍	GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
生物功能	GFAP is a class-III intermediate filament. It is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. [UniProt]
产品亮点	Related products: GFAP antibodies; GFAP Duos / Panels; Anti-Mouse IgM secondary antibodies; Related news: Astrocyte-to-neuron conversion for Parkinson's disease treatment
研究领域	Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody; Astrocyte Marker antibody; Astrocyte Maturation Marker antibody; Neuroinflammation antibody; Brain Injury IHC Study antibody
预测分子量	50 kDa
翻译后修饰	Phosphorylated by PKN1.

检测图片 (1)

ARG62992 anti-GFAP antibody [GF-02] WB image
Western blot: Porcine brain lysate stained with ARG62992 anti-GFAP antibody [GF-02].

Lane 1: immunostaining with anti-GFAP antibody. Lane 2: immunostaining with Isotype mouse IgM control.

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