anti-GH1 / Growth hormone antibody [SPM106]
![anti-GH1 / Growth hormone antibody [SPM106]](/upload/image/products/ARG41410_IHC-P_1_210_205.jpg)
![anti-GH1 / Growth hormone antibody [SPM106]](/upload/image/products/ARG41410_IHC-P_1.jpg)
Key features and details
- 产品描述:
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- 应用:
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- 克隆:
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- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG41410
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [SPM106] recognizes GH1 / Growth hormone |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SPM106 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | GH1 / Growth hormone |
| 抗原物种 | Human |
| 抗原 | Partial recombinant protein corresponding to aa. 58-187 of Human GH1. |
| 偶联标记 | Un-conjugated |
| 別名 | GH-N; Somatotropin; IGHD1B; Growth hormone; Growth hormone 1; Pituitary growth hormone; GHN; hGH-N; GH |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GH1 |
| 全名 | growth hormone 1 |
| 背景介绍 | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (1)
ARG41410 anti-GH1 / Growth hormone antibody [SPM106] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human pituitary gland tissue stained with ARG41410 anti-GH1 / Growth hormone antibody [SPM106]. Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min.
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