anti-GJC2 / Connexin 47 antibody
CAT.NO. : ARG59462
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概述
产品描述 | Rabbit Polyclonal antibody recognizes GJC2 / Connexin 47 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | GJC2 / Connexin 47 |
抗原物种 | Human |
抗原 | Synthetic peptide corresponding to aa. 336-368 of Human GJC2. (VVRAAERARAHDQNLANLALQALRDGAAAGDRD) |
偶联标记 | Un-conjugated |
別名 | CX46.6; Cx47; Gap junction alpha-12 protein; PMLDAR; SPG44; Gap junction gamma-2 protein; GJA12; Connexin-46.6; LMPH1C; Connexin-47; HLD2; Cx46.6 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | GJC2 |
全名 | gap junction protein, gamma 2, 47kDa |
背景介绍 | This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008] |
生物功能 | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. [UniProt] |
细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. [UniProt] |
预测分子量 | 47 kDa |
