anti-GLMN antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GLMN
  • 反应物种: Hu
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GLMN
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide between aa. 498-525 of Human GLMN.
  • Brand:
CAT.NO. : ARG41916
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GLMN
反应物种Hu
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GLMN
抗原物种Human
抗原KLH-conjugated synthetic peptide between aa. 498-525 of Human GLMN.
偶联标记Un-conjugated
別名VMGLOM; GVM; FAP; FKBP-associated protein; Glomulin; FAP48; FK506-binding protein-associated protein; FKBPAP; FAP68; GLML
应用说明
应用建议
应用推荐稀释比
FACS1:10 - 1:50
IHC-P1:10 - 1:50
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照MDA-MB-231
实际分子量~ 68 kDa
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11146 Human GLMN

Swiss-port # Q92990 Human Glomulin

基因名称GLMN
全名glomulin, FKBP associated protein
背景介绍This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
生物功能Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production. [UniProt]
预测分子量68 kDa
翻译后修饰Phosphorylated on tyrosine residues. [UniProt]
检测图片 (3)
  • ARG41916 anti-GLMN antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human bladder carcinoma tissue stained with ARG41916 anti-GLMN antibody.

  • ARG41916 anti-GLMN antibody WB image

    Western blot: 35 µg of MDA-MB-231 cell lysate stained with ARG41916 anti-GLMN antibody.

  • ARG41916 anti-GLMN antibody FACS image

    Flow Cytometry: K562 cells stained with ARG41916 anti-GLMN antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.

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