anti-GLRX3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GLRX3
  • 反应物种: Hu
  • 应用: IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GLRX3
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human GLRX3
  • Brand:
CAT.NO. : ARG56317
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GLRX3
反应物种Hu
应用IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GLRX3
抗原物种Human
抗原Recombinant protein of Human GLRX3
偶联标记Un-conjugated
別名GLRX4; TXNL2; Thioredoxin-like protein 2; PKCq-interacting protein; GRX3; TXNL3; PICOT; Glutaredoxin-3; GRX4; PKC-theta-interacting protein; PKC-interacting cousin of thioredoxin
应用说明
应用建议
应用推荐稀释比
IP
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HeLa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10539 Human GLRX3

Swiss-port # O76003 Human Glutaredoxin-3

基因名称GLRX3
全名glutaredoxin 3
背景介绍This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
生物功能Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. [UniProt]
预测分子量37 kDa
检测图片 (1)
  • ARG56317 anti-GLRX3 antibody WB image

    Western blot: HeLa cell lysate stained with ARG56317 anti-GLRX3 antibody.

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