anti-Glucose 6 phosphate isomerase antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes Glucose 6 phosphate isomerase
  • 反应物种: Hu
  • 应用: IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: Glucose 6 phosphate isomerase
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44668
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes Glucose 6 phosphate isomerase
反应物种Hu
应用IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称Glucose 6 phosphate isomerase
抗原物种Human
偶联标记Un-conjugated
別名GPI; Glucose-6-Phosphate Isomerase; AMF; NLK; Autocrine Motility Factor; Phosphoglucose Isomerase; Phosphohexose Isomerase; Neuroleukin; EC 5.3.1.9; SA-36; PGI; PHI; Hexose Monophosphate Isomerase; Glucose Phosphate Isomerase; Hexosephosphate Isomerase; Phosphosaccharomutase; Phosphohexomutase; Sperm Antigen-36; Sperm Antigen 36; Oxoisomerase; GNPI; SA36
应用说明
应用建议
应用推荐稀释比
IHC-P5-10 µg/mL
IP10 µg/mL
WB1 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2821 Human GPI

Swiss-port # P06744 Human Glucose-6-phosphate isomerase

基因名称GPI
全名Glucose-6-Phosphate Isomerase
背景介绍This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
生物功能Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons.

It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. [UniProt]
细胞定位Cytoplasm, Secreted. [UniProt]
预测分子量63 kDa
翻译后修饰Acetylation, Hydroxylation, Phosphoprotein, Ubl conjugation. [UniProt]
检测图片 (3)
  • ARG44668 anti-Glucose 6 phosphate isomerase antibody IHC-P image

    Immunohistochemistry: Human Colon stained with ARG44668 anti-Glucose 6 phosphate isomerase antibody at 1 µg/mL dilution.

  • ARG44668 anti-Glucose 6 phosphate isomerase antibody WB image

    Western blot: MCF7, A549, HeLa, HepG2 stained with ARG44668 anti-Glucose 6 phosphate isomerase antibody at 1 µg/mL dilution.

  • ARG44668 anti-Glucose 6 phosphate isomerase antibody IP image

    Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44668 anti-Glucose 6 phosphate isomerase antibody.

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