anti-Glucose 6 phosphate isomerase antibody
CAT.NO. : ARG44668
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概述
产品描述 | Mouse Monoclonal antibody recognizes Glucose 6 phosphate isomerase |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | Glucose 6 phosphate isomerase |
抗原物种 | Human |
偶联标记 | Un-conjugated |
別名 | GPI; Glucose-6-Phosphate Isomerase; AMF; NLK; Autocrine Motility Factor; Phosphoglucose Isomerase; Phosphohexose Isomerase; Neuroleukin; EC 5.3.1.9; SA-36; PGI; PHI; Hexose Monophosphate Isomerase; Glucose Phosphate Isomerase; Hexosephosphate Isomerase; Phosphosaccharomutase; Phosphohexomutase; Sperm Antigen-36; Sperm Antigen 36; Oxoisomerase; GNPI; SA36 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | GPI |
全名 | Glucose-6-Phosphate Isomerase |
背景介绍 | This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
生物功能 | Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. [UniProt] |
细胞定位 | Cytoplasm, Secreted. [UniProt] |
预测分子量 | 63 kDa |
翻译后修饰 | Acetylation, Hydroxylation, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (3)
ARG44668 anti-Glucose 6 phosphate isomerase antibody IHC-P image
Immunohistochemistry: Human Colon stained with ARG44668 anti-Glucose 6 phosphate isomerase antibody at 1 µg/mL dilution.
ARG44668 anti-Glucose 6 phosphate isomerase antibody WB image
Western blot: MCF7, A549, HeLa, HepG2 stained with ARG44668 anti-Glucose 6 phosphate isomerase antibody at 1 µg/mL dilution.
ARG44668 anti-Glucose 6 phosphate isomerase antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44668 anti-Glucose 6 phosphate isomerase antibody.
