anti-Glycophorin C antibody
Key features and details
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- 抗原:
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Brand:
CAT.NO. : ARG41483
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Glycophorin C |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Glycophorin C |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-128 of Human Glycophorin C (NP_002092.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Glycophorin-D; CD236R; GPD; Glycophorin-C; Glycoprotein beta; Glycoconnectin; GPC; PAS-2; CD antigen CD236; GE; CD236; Sialoglycoprotein D; GYPD; PAS-2' |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HepG2 | ||||
| 实际分子量 | ~ 34 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GYPC |
| 全名 | glycophorin C (Gerbich blood group) |
| 背景介绍 | Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] |
| 生物功能 | This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type III membrane protein. Note=Linked to the membrane via band 4.1. [UniProt] |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | O-glycosylated with core 1 or possibly core 8 glycans. [UniProt] |
检测图片 (1)
ARG41483 anti-Glycophorin C antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG41483 anti-Glycophorin C antibody at 1:1000 dilution.
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