anti-GnRHR / GnRH Receptor antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG64079
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes GnRHR / GnRH Receptor |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise both reported isoforms (NP_000397.1; NP_001012781.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GnRHR / GnRH Receptor |
| 抗原物种 | Human |
| 抗原 | C-QKWTQKKEKGK |
| 偶联标记 | Un-conjugated |
| 別名 | GRHR; HH7; LRHR; LHRHR; Gonadotropin-releasing hormone receptor; GnRH receptor; GNRHR1; GnRH-R |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P30968 Human Gonadotropin-releasing hormone receptor |
|---|---|
| 背景介绍 | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 38 kDa |
检测图片 (1)
ARG64079 anti-GnRHR / GnRH Receptor antibody WB image
Western blot: 35 µg of Human Peripheral Blood Mononucleocyte lysate stained with ARG64079 anti-GnRHR / GnRH Receptor antibody at 0.5 µg/ml and 1 hour incubation.
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