anti-GNS antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58783
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GNS |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GNS |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to W238-R355 of Human GNS. |
| 偶联标记 | Un-conjugated |
| 別名 | G6S; EC 3.1.6.14; Glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GNS |
| 全名 | glucosamine (N-acetyl)-6-sulfatase |
| 背景介绍 | The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | 62 kDa |
| 翻译后修饰 | The form A (78 kDa) is processed by internal peptidase cleavage to a 32 kDa N-terminal species (form B) and a 48 kDa C-terminal species. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. [UniProt] |
检测图片 (2)
ARG58783 anti-GNS antibody WB image
Western blot: 50 µg of samples under reducing conditions. HepG2, PANC-1 and SGC-7901 cell lysates stained with ARG58783 anti-GNS antibody at 0.5 µg/ml, overnight at 4°C.
ARG58783 anti-GNS antibody WB image
Western blot: 50 µg of samples under reducing conditions. Rat lung, Rat kidney, Rat testis, PC-12, Mouse lung, Mouse kidney, Mouse testis, Mouse spleen and Mouse thymus lysates stained with ARG58783 anti-GNS antibody at 0.5 µg/ml, overnight at 4°C.
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