anti-GOPC / PIST antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GOPC / PIST
  • 反应物种: Rat
  • 预测物种: Hu, Ms
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GOPC / PIST
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG55411
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GOPC / PIST
反应物种Rat
预测物种Hu, Ms
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GOPC / PIST
抗原物种Human
抗原Synthetic peptide (16 aa) within aa. 360-410 of Human PIST.
偶联标记Un-conjugated
別名Golgi-associated PDZ and coiled-coil motif-containing protein; Fused in glioblastoma; dJ94G16.2; CFTR-associated ligand; FIG; CAL; PIST; PDZ protein interacting specifically with TC10; GOPC1
应用说明
应用建议
应用推荐稀释比
ICC/IF10 μg/ml
IHC-P1 μg/ml
WB1 - 4 μg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat Colon Lysate
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称GOPC
全名golgi-associated PDZ and coiled-coil motif containing
背景介绍This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
生物功能Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. [UniProt]
研究领域Controls and Markers antibody; Signaling Transduction antibody
预测分子量51 kDa
检测图片 (3)
  • ARG55411 anti-GOPC / PIST antibody WB image

    Western blot: Rat colon cell lysate stained with ARG55411 anti-GOPC / PIST antibody at (A) 1, (B) 2 and (C) 4 µg/ml dilution.

  • ARG55411 anti-GOPC / PIST antibody IHC image

    Immunohistochemistry: Rat colon tissue stained with ARG55411 anti-GOPC / PIST antibody at 1 µg/ml dilution.

  • ARG55411 anti-GOPC / PIST antibody ICC/IF image

    Immunofluorescence: Rat Colon cells stained with ARG55411 anti-GOPC / PIST antibody at 10 µg/ml dilution.

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