anti-GPBB + GPMM antibody [17B6]
![anti-GPBB + GPMM antibody [17B6]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
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CAT.NO. : ARG10371
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [17B6] recognizes GPBB + GPMM |
|---|---|
| 反应物种 | Hu |
| 应用 | Puri, WB |
| 特异性 | This antibody recognizes BB and MM isoenzymes. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 17B6 |
| 同位型 | IgG1 |
| 靶点名称 | GPBB + GPMM |
| 抗原物种 | Human |
| 抗原 | Human GPBB. |
| 偶联标记 | Un-conjugated |
| 別名 | GPBB; EC 2.4.1.1; Glycogen phosphorylase, brain form |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4) and 0.1% Sodium azide |
| 抗菌剂 | 0.1% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P11216 Human Glycogen phosphorylase, brain form |
|---|---|
| 基因名称 | PYGB |
| 全名 | phosphorylase, glycogen; brain |
| 背景介绍 | The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. [UniProt] |
| 预测分子量 | 97 kDa |
| 翻译后修饰 | Phosphorylated (PubMed:27402852). Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity). |
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