anti-GPM6A antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG59645
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GPM6A |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Cow, Dog, Gpig, Hrs, Rb, Zfsh |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GPM6A |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the C-terminal region of Human GPM6A. (within the following region: IAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLN) |
| 偶联标记 | Un-conjugated |
| 別名 | M6A; Neuronal membrane glycoprotein M6-a; GPM6; M6a |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Zebrafish: 100% | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P51674 Human Neuronal membrane glycoprotein M6-a |
|---|---|
| 基因名称 | GPM6A |
| 全名 | glycoprotein M6A |
| 生物功能 | Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons (By similarity). [UniProt] |
| 预测分子量 | 31 kDa |
检测图片 (4)
ARG59645 anti-GPM6A antibody ICC/IF image
Immunofluorescence: Rat hippocampal culture neurons stained with ARG59645 anti-GPM6A antibody (green) at 1:250 dilution. DAPI (blue) for nuclear staining.
ARG59645 anti-GPM6A antibody WB image
Western blot: 250 µg, 200 µg, 100 µg and 50 µg of Rat hippocampal culture neurons stained with ARG59645 anti-GPM6A antibody at 1:1000 dilution.
ARG59645 anti-GPM6A antibody WB image
Western blot: 400 µg, 300 µg, 200 µg and 100 µg of Rat hippocampal stained with ARG59645 anti-GPM6A antibody at 1:1000 dilution.
ARG59645 anti-GPM6A antibody WB image
Western blot: Human brain lysates stained with ARG59645 anti-GPM6A antibody at 1.0 µg/ml dilution.
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