anti-GPR2 / CCR10 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes GPR2 / CCR10
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Hm
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: GPR2 / CCR10
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG58807
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes GPR2 / CCR10
反应物种Hu
预测物种Ms, Rat, Hm
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称GPR2 / CCR10
抗原物种Human
抗原Synthetic peptide corresponding to aa. 312-327 of Human GPR2 / CCR10 (FLGLRFRQDLRRLLRG).
偶联标记Un-conjugated
別名GPR2; CC-CKR-10; CCR-10; C-C CKR-10; G-protein coupled receptor 2; C-C chemokine receptor type 10
应用说明
应用建议
应用推荐稀释比
WB0.1 - 0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Thimerosal and 0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2826 Human CCR10

Swiss-port # P46092 Human C-C chemokine receptor type 10

基因名称CCR10
全名chemokine (C-C motif) receptor 10
背景介绍Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
生物功能Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. [UniProt]
细胞定位Cell membrane; Multi-pass membrane protein. [UniProt]
预测分子量38 kDa
检测图片 (1)
  • ARG58807 anti-GPR2 / CCR10 antibody WB image

    Western blot: HeLa, SW620, A549, MDA-MB-231 and SMMC-7721 cell lysates stained with ARG58807 anti-GPR2 / CCR10 antibody.

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