anti-GPR77 / C5L2 antibody [1D9-M12] (APC)

CAT.NO. : ARG44591

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Size:

100 tests

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Product Details

概述

产品描述	APC-conjugated Mouse Monoclonal antibody recognizes GPR77 / C5L2
反应物种	Hu
应用	FACS
宿主	Mouse
克隆	Monoclonal
克隆号	1D9-M12
同位型	IgG2a kappa
靶点名称	GPR77 / C5L2
抗原物种	Human
偶联标记	APC
別名	C5AR2; Complement C5a Receptor 2; C5L2; Complement Component 5a Receptor 2; GPR77; C5a Anaphylatoxin Chemotactic Receptor 2; G Protein-Coupled Receptor 77; C5a Anaphylatoxin Chemotactic Receptor C5L2; G Protein-Coupled Receptor C5L2; G-Protein Coupled Receptor 77; GPF77

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 27202 Human C5AR2 Swiss-port # Q9P296 Human C5a anaphylatoxin chemotactic receptor 2
基因名称	C5AR2
全名	complement component 5a receptor 2
背景介绍	This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
生物功能	Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. [UniProt]
细胞定位	Cell membrane, Membrane. [UniProt]
预测分子量	36 kDa
翻译后修饰	Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt]

检测图片 (1)

ARG44591 anti-GPR77 / C5L2 antibody [1D9-M12] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44591 anti-GPR77 / C5L2 antibody [1D9-M12] (APC) at 10 μl/ 100 μl dilution.

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