anti-GRAF / ARHGAP26 antibody
CAT.NO. : ARG63557
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概述
产品描述 | Goat Polyclonal antibody recognizes GRAF / ARHGAP26 |
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反应物种 | Hu |
预测物种 | Ms, Rat, Cow, Dog |
应用 | IHC-P, WB |
特异性 | This antibody is expected to recognise both reported isoforms. |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | GRAF / ARHGAP26 |
抗原物种 | Human |
抗原 | C-KTGLIPENYVEFL |
偶联标记 | Un-conjugated |
別名 | Rho-type GTPase-activating protein 26; OPHN1L1; Rho GTPase-activating protein 26; OPHN1L; Oligophrenin-1-like protein; GRAF1; GTPase regulator associated with focal adhesion kinase; GRAF |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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背景介绍 | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] |
研究领域 | Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody |
预测分子量 | 92 kDa |
检测图片 (2)
ARG63557 anti-GRAF / ARHGAP26 antibody WB image
Western Blot: Human Heart lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. stained with ARG63557 anti-GRAF / ARHGAP26 antibody at 0.3 µg/ml dilution.
ARG63557 anti-GRAF / ARHGAP26 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human colon tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63557 anti-GRAF / ARHGAP26 antibody at 3.75 µg/ml dilution followed by AP-staining.
