anti-GRP94 antibody [94B9]

CAT.NO. : ARG57042

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [94B9] recognizes GRP94
反应物种	Hu
应用	FACS, ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	94B9
同位型	IgG2b, kappa
靶点名称	GRP94
抗原物种	Human
抗原	Recombinant fragment around aa. 22-803 of Human GPR94.
偶联标记	Un-conjugated
別名	Tumor rejection antigen 1; gp96 homolog; Endoplasmin; 94 kDa glucose-regulated protein; HEL-S-125m; GP96; GRP94; TRA1; HEL35; GRP-94; Heat shock protein 90 kDa beta member 1; ECGP

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7184 Human HSP90B1 Swiss-port # P14625 Human Endoplasmin
基因名称	HSP90B1
全名	heat shock protein 90kDa beta (Grp94), member 1
背景介绍	This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]
生物功能	Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. [UniProt]
预测分子量	92 kDa

检测图片 (3)

ARG57042 anti-GRP94 antibody [94B9] ICC/IF image
Immunoflorescense: U87MG cell line stained with ARG57042 anti-GRP94 antibody [94B9] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57042 anti-GRP94 antibody [94B9] FACS image
Flow Cytometry: U87MG cell line stained with ARG57042 anti-GRP94 antibody [94B9] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57042 anti-GRP94 antibody [94B9] WB image
Western blot: 1) 25 ng of Recombinant Human GRP94, 40 µg of 2) HeLa cell lysate, 3) Jurkat cell lysate, 4) HepG2 cell lysate stained with ARG57042 anti-GRP94 antibody [94B9] at 1:3000.

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