anti-GSDMC antibody
CAT.NO. : ARG42638
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GSDMC |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GSDMC |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-100 of Human GSDMC (NP_113603.1). |
| 偶联标记 | Un-conjugated |
| 別名 | MLZE; Melanoma-derived leucine zipper-containing extranuclear factor; Gasdermin-C |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa | ||||||
| 实际分子量 | ~ 58 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GSDMC |
| 全名 | gasdermin C |
| 生物功能 | The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt] |
| 产品亮点 | Related news: Solutions for studying PANoptosis & PANoptosome |
| 预测分子量 | 58 kDa |
检测图片 (2)
ARG42638 anti-GSDMC antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG42638 anti-GSDMC antibody at 1:100 dilution. DAPI (blue) for nuclear staining.
ARG42638 anti-GSDMC antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG42638 anti-GSDMC antibody at 1:3000 dilution.
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