anti-Guanylate Cyclase C antibody
CAT.NO. : ARG10785
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Guanylate Cyclase C |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Guanylate Cyclase C |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide around the C-terminus from Rat Guanylyl cyclase C. |
| 偶联标记 | Un-conjugated |
| 別名 | MECIL; STAR; STA receptor; MUCIL; hSTAR; Heat-stable enterotoxin receptor; Intestinal guanylate cyclase; Guanylyl cyclase C; GUC2C; EC 4.6.1.2; DIAR6; GC-C |
应用说明
| 应用建议 |
| ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.65 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Gucy2c |
| 全名 | guanylate cyclase 2C |
| 生物功能 | Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [UniProt] |
| 预测分子量 | 123 kDa |
| 翻译后修饰 | Glycosylation at Asn-75 and/or Asn-79 is required for interaction with VIP36 while glycosylation at Asn-345 and Asn-402 modulates ligand-mediated GC-C activation. |
检测图片 (2)
ARG10785 anti-Guanylate Cyclase C antibody IHC image
Immunohistochemistry: Thin section of Mouse small intestine stained with ARG10785 anti-Guanylate Cyclase C antibody (red). Blue: Nuclei.
ARG10785 anti-Guanylate Cyclase C antibody WB image
Western blot: Recombinant Guanylyl cyclase C protein stained with ARG10785 anti-Guanylate Cyclase C antibody at 1:500 dilution.
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