anti-Guanylate Cyclase C antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Guanylate Cyclase C
  • 反应物种: Hu, Ms, Rat
  • 应用: Confocal, Dot, ELISA, ICC/IF, IHC, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Guanylate Cyclase C
  • 抗原物种: Rat
  • 抗原: Synthetic peptide around the C-terminus from Rat Guanylyl cyclase C.
  • Brand:
CAT.NO. : ARG10785
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Guanylate Cyclase C
反应物种Hu, Ms, Rat
应用Confocal, Dot, ELISA, ICC/IF, IHC, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Guanylate Cyclase C
抗原物种Rat
抗原Synthetic peptide around the C-terminus from Rat Guanylyl cyclase C.
偶联标记Un-conjugated
別名MECIL; STAR; STA receptor; MUCIL; hSTAR; Heat-stable enterotoxin receptor; Intestinal guanylate cyclase; Guanylyl cyclase C; GUC2C; EC 4.6.1.2; DIAR6; GC-C
应用说明
应用建议
应用推荐稀释比
Confocal1:200
Dot1:10000
ELISA1:10000
ICC/IF1:200
IHC1:200
WB1:500
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂30% Glycerol and 0.5% BSA
浓度0.65 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14917 Mouse GUCY2C

GeneID: 2984 Human GUCY2C

Swiss-port # P25092 Human Heat-stable enterotoxin receptor

Swiss-port # Q3UWA6 Mouse Heat-stable enterotoxin receptor

基因名称Gucy2c
全名guanylate cyclase 2C
生物功能Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [UniProt]
预测分子量123 kDa
翻译后修饰Glycosylation at Asn-75 and/or Asn-79 is required for interaction with VIP36 while glycosylation at Asn-345 and Asn-402 modulates ligand-mediated GC-C activation.
检测图片 (2)
  • ARG10785 anti-Guanylate Cyclase C antibody IHC image

    Immunohistochemistry: Thin section of Mouse small intestine stained with ARG10785 anti-Guanylate Cyclase C antibody (red). Blue: Nuclei.

  • ARG10785 anti-Guanylate Cyclase C antibody WB image

    Western blot: Recombinant Guanylyl cyclase C protein stained with ARG10785 anti-Guanylate Cyclase C antibody at 1:500 dilution.

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