Anti-H10N3 Avian Influenza HA Protein Mouse Monoclonal Antibody (H10_1F4)
Key features and details
- Product:
- Clone:
- Host:
- Species Reactivity:
- Application:
- Immunogen :
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0009
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Size:
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Product Details
Background
The H10N3 Avian Influenza HA Protein (Hemagglutinin Protein) is a key surface glycoprotein of the H10N3 avian influenza virus, playing an indispensable role in viral entry into host cells and immune recognition. It belongs to class I viral fusion proteins and exists as a homotrimer, with each monomer processed from a precursor (HA0) into two functional subunits (HA1 and HA2) via cleavage by host proteases. The HA1 subunit contains a conserved receptor-binding site (RBS) that specifically binds to α-2,3-linked sialic acid receptors—predominantly expressed on avian respiratory and intestinal epithelial cells. This binding event is the initial step of viral attachment, enabling the virus to anchor to target cells. The HA2 subunit, embedded in the viral envelope, mediates the fusion of the viral membrane with the host cell endosomal membrane through pH-dependent conformational changes, facilitating the release of the viral genome into the cytoplasm for replication.
Application
|
Application |
Recommended Dilution Ratio |
|
WB |
1:200-1:1000 |
|
IFA |
1:20-1:500 |
|
HI |
1:1000-1:2048 |
Overview
|
Host |
Mouse |
|
Clonality |
Monoclonal |
|
Applications |
WB, IFA |
|
Reactivity |
H9N2 Avian Influenza HA Protein |
|
Appearance |
Liquid |
|
Storage Buffer |
PBS, 20% Glycerol; containing 0.05% Sodium Azide as preservative |
|
Storage Conditions |
Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
|
Immunogen |
H9N2 Avian Influenza Virus |
Data
WB and IFA results demonstrate that this antibody can effectively recognize the H9N2 HA Protein.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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