Anti-H3N8 Avian Influenza HA Protein Mouse Monoclonal Antibody (H3_4C2)
Key features and details
- Product:
- Clone:
- Host:
- Species Reactivity:
- Application:
- Immunogen :
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0003
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
The H3N8 Avian Influenza HA Protein (Hemagglutinin Protein) is a pivotal surface glycoprotein of the H3N8 avian influenza virus, playing a decisive role in viral entry into host cells. As a class I fusion protein, it exists as a stable homotrimer, with each monomer consisting of two functional subunits (HA1 and HA2) linked by disulfide bonds. The HA1 subunit contains the receptor-binding site (RBS), which specifically recognizes and binds to sialic acid receptors on the surface of host epithelial cells—this binding is the initial step of viral attachment. The HA2 subunit, anchored in the viral envelope, mediates the fusion of the viral membrane with the host cell endosomal membrane through pH-induced conformational changes, allowing the viral genome to enter the host cytoplasm for replication.
Application
|
Application |
Recommended Dilution Ratio |
|
WB |
1:200:1:1000 |
|
IF |
1:50-1:500 |
|
HI |
1:1000-1:5120 |
Overview
|
Host |
Mouse |
|
Clonality |
Monoclonal |
|
Applications |
WB (Western Blot), IFA (Indirect Immunofluorescence Assay), HI (Hemagglutination Inhibition Assay) |
|
Reactivity |
H3N8 Avian Influenza HA Protein |
|
Appearance |
Liquid |
|
Storage Buffer |
PBS (Phosphate Buffered Saline) containing 20% glycerol; 0.05% Sodium Azide as preservative |
|
Storage Conditions |
Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
|
Immunogen |
H3N8 Avian Influenza Virus HA Protein |
Data
WB and IFA results indicate that this antibody can effectively recognize the H3N8 HA protein expressed in 293T cells.
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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