Anti-H6N2 Avian Influenza HA Protein Mouse Monoclonal Antibody (H6_5G2)
Key features and details
- Product:
- Clone:
- Host:
- Species Reactivity:
- Application:
- Immunogen :
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0007
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
The H6N2 Avian Influenza HA Protein (Hemagglutinin Protein) is a key surface glycoprotein of the H6N2 avian influenza virus, playing a pivotal role in viral entry into host cells and pathogenesis. It belongs to class I viral fusion proteins and exists as a stable homotrimer, with each monomer composed of two non-covalently linked subunits (HA1 and HA2) that are cleaved from a precursor polypeptide (HA0) by host proteases. The HA1 subunit contains a conserved receptor-binding site (RBS) that specifically recognizes and binds to α-2,3-linked sialic acid receptors—predominantly expressed on the surface of avian respiratory and intestinal epithelial cells. This binding is the initial step of viral attachment, enabling the virus to anchor to target cells. The HA2 subunit, spanning the viral envelope, mediates the fusion of the viral membrane with the host cell endosomal membrane through pH-dependent conformational changes, facilitating the release of the viral genome into the host cytoplasm for replication.
Application
|
Application |
Recommended Dilution Ratio |
|
WB |
1:200-1:1000 |
|
IF |
1:200-1:1000 |
|
HI |
1:1000-1:2048 |
*The optimal dilution/concentration should be determined by the researcher.
Overview
|
Host |
Mouse |
|
Clonality |
Monoclonal |
|
Applications |
WB (Western Blot), IFA (Indirect Immunofluorescence Assay), HI (Hemagglutination Inhibition Assay) |
|
Reactivity |
H6N2 Avian Influenza HA Protein |
|
Appearance |
Liquid |
|
Storage Buffer |
PBS (Phosphate Buffered Saline), 20% Glycerol; containing 0.05% Sodium Azide as preservative |
|
Storage Conditions |
Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
|
Immunogen |
H6N2 Avian Influenza Virus |
Data
WB and IFA results indicate that this antibody can effectively recognize the H6N2 HA protein expressed in 293T cells.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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