anti-HARS antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57450
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes HARS |
|---|---|
| 反应物种 | Hu, Mk |
| 应用 | WB |
| 特异性 | This antibody detects endogenous levels of HARS and does not cross-react with related proteins. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | HARS |
| 抗原物种 | Human |
| 抗原 | Purified recombinant Human HARS protein fragments expressed in E. coli. |
| 偶联标记 | Un-conjugated |
| 別名 | HisRS; USH3B; EC 6.1.1.21; Histidyl-tRNA synthetase; Histidine-tRNA ligase, cytoplasmic; HRS |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.03% Proclin300 and 50% Glycerol. |
| 抗菌剂 | 0.03% Proclin300 |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1.1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P12081 Human Histidine--tRNA ligase, cytoplasmic |
|---|---|
| 基因名称 | HARS |
| 全名 | histidyl-tRNA synthetase |
| 背景介绍 | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| 细胞定位 | Cytoplasm. |
| 预测分子量 | 57 kDa |
检测图片 (1)
ARG57450 anti-HARS antibody WB image
Western blot: HeLa cell lysate stained with ARG57450 anti-HARS antibody at 1:2000 dilution.
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