anti-HAS3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes HAS3
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: HAS3
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 67-281 of Human HAS3 (NP_619515.1).
  • Brand:
CAT.NO. : ARG59604
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes HAS3
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称HAS3
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 67-281 of Human HAS3 (NP_619515.1).
偶联标记Un-conjugated
別名HA synthase 3; EC 2.4.1.212; Hyaluronic acid synthase 3; Hyaluronate synthase 3; Hyaluronan synthase 3
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat heart, Mouse heart and SW480
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15118 Mouse HAS3

GeneID: 3038 Human HAS3

Swiss-port # O00219 Human Hyaluronan synthase 3

Swiss-port # O08650 Mouse Hyaluronan synthase 3

基因名称HAS3
全名hyaluronan synthase 3
背景介绍The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
生物功能Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity). [UniProt]
细胞定位Membrane; Multi-pass membrane protein. [UniProt]
预测分子量63 kDa
检测图片 (1)
  • ARG59604 anti-HAS3 antibody ICC/IF image

    Immunofluorescence: A549 cells stained with ARG59604 anti-HAS3 antibody.

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