anti-HAX1 antibody [3C5]

CAT.NO. : ARG57096

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [3C5] recognizes HAX1
反应物种	Hu
应用	ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	3C5
同位型	IgG2b, kappa
靶点名称	HAX1
抗原物种	Human
抗原	Recombinant fragment around aa. 1-279 of Human HAX1
偶联标记	Un-conjugated
別名	HCLS1-associated protein X-1; HS1BP1; HAX-1; HS1-binding protein 1; HS1-associating protein X-1; HSP1BP-1; SCN3; HCLSBP1

应用说明

应用建议

应用	推荐稀释比
ICC/IF	Assay-dependent
WB	1:1000 - 1:2000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10456 Human HAX1 Swiss-port # O00165 Human HCLS1-associated protein X-1
基因名称	HAX1
全名	HCLS1 associated protein X-1
背景介绍	The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools. [UniProt]
预测分子量	32 kDa
翻译后修饰	Proteolytically cleaved by caspase-3 during apoptosis.

检测图片 (3)

ARG57096 anti-HAX1 antibody [3C5] ICC/IF image
Immunofluorescence: HeLa cells line stained with ARG57096 anti-HAX1 antibody [3C5] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57096 anti-HAX1 antibody [3C5] WB image
Western blot: 30 µg of HeLa cell lysate stained with ARG57096 anti-HAX1 antibody [3C5] at 1:1000.
ARG57096 anti-HAX1 antibody [3C5] WB image
Western blot: 40 µg of Raji cell lysate stained with ARG57096 anti-HAX1 antibody [3C5] at 1:1000.

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