anti-HAX1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes HAX1
  • 反应物种: Hu
  • 应用: WB
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_006109.2 and NP_001018238.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: HAX1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64853
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes HAX1
反应物种Hu
应用WB
特异性This antibody is expected to recognize both reported isoforms (NP_006109.2 and NP_001018238.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称HAX1
抗原物种Human
抗原C-TRHEADSSPRGDPES
偶联标记Un-conjugated
別名HCLS1-associated protein X-1; HS1BP1; HAX-1; HS1-binding protein 1; HS1-associating protein X-1; HSP1BP-1; SCN3; HCLSBP1
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10456 Human HAX1

Swiss-port # O00165 Human HCLS1-associated protein X-1

背景介绍The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
预测分子量32 kDa
翻译后修饰Proteolytically cleaved by caspase-3 during apoptosis.
检测图片 (1)
  • ARG64853 anti-HAX1 antibody WB image

    Western Blot: Human Testis lysate (35 µg protein in RIPA buffer) stained with ARG64853 anti-HAX1 antibody at 1 µg/ml dilution.

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