anti-HCLS1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes HCLS1
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: HCLS1
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 1-280 of Human HCLS1 (NP_005326.2).
  • Brand:
CAT.NO. : ARG57756
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes HCLS1
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称HCLS1
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 1-280 of Human HCLS1 (NP_005326.2).
偶联标记Un-conjugated
別名p75; LckBP1; Hematopoietic cell-specific LYN substrate 1; HS1; Hematopoietic lineage cell-specific protein; CTTNL; lckBP1
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Jurkat
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15163 Mouse HCLS1

GeneID: 3059 Human HCLS1

Swiss-port # P14317 Human Hematopoietic lineage cell-specific protein

Swiss-port # P49710 Mouse Hematopoietic lineage cell-specific protein

基因名称HCLS1
全名hematopoietic cell-specific Lyn substrate 1
生物功能Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]
细胞定位Cytoplasm, Membrane, Mitochondrion, Peripheral membrane protein. [UniProt]
预测分子量54 kDa
翻译后修饰Phosphorylated by FES (By similarity). Phosphorylated by LYN, FYN and FGR after cross-linking of surface IgM on B-cells. Phosphorylation by LYN, FYN and FGR requires prior phosphorylation by SYK or FES. [UniProt]
检测图片 (2)
  • ARG57756 anti-HCLS1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney stained with ARG57756 anti-HCLS1 antibody at 1:100 dilution.

  • ARG57756 anti-HCLS1 antibody WB image

    Western blot: 25 µg of Jurkat cell lysate stained with ARG57756 anti-HCLS1 antibody at 1:1000 dilution.

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