anti-HCN1 antibody [S70-28]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [S70-28] recognizes HCN1
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC, IP, WB
  • 特异性: Detects ~100kDa. No cross-reactivity against HCN2.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: S70-28
  • 同位型: IgG1
  • 靶点名称: HCN1
  • Brand:
CAT.NO. : ARG22222
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Product Details
概述
产品描述Mouse Monoclonal antibody [S70-28] recognizes HCN1
反应物种Hu, Ms, Rat
应用IHC, IP, WB
特异性Detects ~100kDa. No cross-reactivity against HCN2.
宿主Mouse
克隆Monoclonal
克隆号S70-28
同位型IgG1
靶点名称HCN1
抗原物种Rat
抗原Fusion protein around aa. 778-910 (C terminus) of Rat HCN1
偶联标记Un-conjugated
別名EIEE24; Brain cyclic nucleotide-gated channel 1; HAC-2; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1; BCNG-1; BCNG1
应用说明
应用建议
应用推荐稀释比
IHC1:1000
IPAssay-dependent
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
抗菌剂0.09% Sodium azide
稳定剂50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15165 Mouse HCN1

GeneID: 348980 Human HCN1

GeneID: 84390 Rat HCN1

基因名称Hcn1
全名hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
背景介绍The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011]
生物功能Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli. [UniProt]
细胞定位Membrane
预测分子量99 kDa
检测图片 (4)
  • ARG22222 anti-HCN1 antibody [S70-28] IHC-Fr image

    Immunohistochemistry: 10% Formalin (12-24 hours at RT) fixed Mouse frozen brain section stained with ARG22222 anti-HCN1 Antibody [S70-28] (brown) at 1:1000 dilution (1 hour). Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500uL for 5 minutes at RT.

  • ARG22222 anti-HCN1 antibody [S70-28] WB image

    Western blot: Rat brain membrane lysate stained with ARG22222 anti-HCN1 Antibody [S70-28] at 1:1000 dilution.

  • ARG22222 anti-HCN1 antibody [S70-28] IHC-Fr image

    Immunohistochemistry: 10% Formalin (12-24 hours at RT) fixed Mouse frozen brain section stained with ARG22222 anti-HCN1 Antibody [S70-28] (brown) at 1:1000 dilution (1 hour). Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500uL for 5 minutes at RT.

  • ARG22222 anti-HCN1 antibody [S70-28] IHC image

    Immunohistochemistry: 10% Formalin (12-24 hours at RT) fixed Mouse Cerebellum stained with ARG22222 anti-HCN1 Antibody [S70-28] (brown) at 1:1000 dilution (1 hour). Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500uL for 5 minutes at RT.

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