anti-HDAC6 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG20183
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HDAC6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC, WB |
| 特异性 | The antibody detects ~134 kDa HDAC-6. The antibody does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 5, 7, and 8. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HDAC6 |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide mapping to the N-terminus of mouse HDAC-6 |
| 偶联标记 | Un-conjugated |
| 別名 | HD6; EC 3.5.1.98; PPP1R90; CPBHM; JM21; Histone deacetylase 6 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | |Jurkat cell lysate can be used as a positive control. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified Antibody |
| 缓冲液 | PBS (pH 7.2), 30% Glycerol, 0.5% BSA and 0.01% Thimerosal |
| 抗菌剂 | 0.01% Thimerosal |
| 稳定剂 | 30% Glycerol, 0.5% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HDAC6 |
| 全名 | histone deacetylase 6 |
| 背景介绍 | Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation. |
| 预测分子量 | 131 kDa |
检测图片 (1)
ARG20183 anti-HDAC6 antibody WB image
Western Blot: Jurkat cell lysate stained with anti-HDAC6 antibody (ARG20183).
The antibody detects ~134 kDa HDAC-6. Jurkat cell lysate can be used as a positive control. The antibody does not cross-react with other HDAC proteins includi ng HDAC1, 2, 3, 4, 5, 7, and 8.
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