anti-HEC1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes HEC1
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: HEC1
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human HEC1.
  • Brand:
CAT.NO. : ARG41383
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes HEC1
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称HEC1
抗原物种Human
抗原Synthetic peptide derived from Human HEC1.
偶联标记Un-conjugated
別名Kinetochore-associated protein 2; TID3; hsNDC80; HEC1; KNTC2; Kinetochore protein NDC80 homolog; Highly expressed in cancer protein; HEC; Retinoblastoma-associated protein HEC; HsHec1; Kinetochore protein Hec1
应用说明
应用建议
应用推荐稀释比
WB1:1000 - 1:5000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 75 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10403 Human NDC80

GeneID: 67052 Mouse NDC80

Swiss-port # O14777 Human Kinetochore protein NDC80 homolog

Swiss-port # Q9D0F1 Mouse Kinetochore protein NDC80 homolog

基因名称NDC80
全名NDC80 kinetochore complex component
背景介绍This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]
生物功能Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. [UniProt]
细胞定位Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. [UniProt]
预测分子量74 kDa
翻译后修饰Phosphorylation begins in S phase of the cell cycle and peaks in mitosis. Phosphorylated by NEK2. May also be phosphorylated by AURKA and AURKB. [UniProt]
检测图片 (1)
  • ARG41383 anti-HEC1 antibody WB image

    Western blot: Jurkat cell lysate stained with ARG41383 anti-HEC1 antibody.

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