anti-HELLS / SMARCA6 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes HELLS / SMARCA6
  • 反应物种: Hu, Ms, Rat
  • 应用: IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: HELLS / SMARCA6
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 719-838 of Human HELLS / SMARCA6 (NP_060533.2).
  • Brand:
CAT.NO. : ARG58963
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes HELLS / SMARCA6
反应物种Hu, Ms, Rat
应用IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称HELLS / SMARCA6
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 719-838 of Human HELLS / SMARCA6 (NP_060533.2).
偶联标记Un-conjugated
別名SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; PASG; Nbla10143; EC 3.6.4.-; LSH; Lymphoid-specific helicase; Proliferation-associated SNF2-like protein; SMARCA6
应用说明
应用建议
应用推荐稀释比
IP1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照MCF7
实际分子量120 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15201 Mouse HELLS

GeneID: 3070 Human HELLS

Swiss-port # Q60848 Mouse Lymphocyte-specific helicase

Swiss-port # Q9NRZ9 Human Lymphoid-specific helicase

基因名称HELLS
全名helicase, lymphoid-specific
背景介绍This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]
生物功能Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity). [UniProt]
细胞定位Nucleus. [UniProt]
预测分子量97 kDa
检测图片 (2)
  • ARG58963 anti-HELLS / SMARCA6 antibody WB image

    Western blot: 25 µg of MCF7 cell lysate stained with ARG58963 anti-HELLS / SMARCA6 antibody at 1:1000 dilution.

  • ARG58963 anti-HELLS / SMARCA6 antibody IP image

    Immunoprecipitation: 200 µg extracts of 293T cells were immunoprecipitated and stained with ARG58963 anti-HELLS / SMARCA6 antibody at 1:1000 dilution.

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