anti-HIP1R antibody
CAT.NO. : ARG44843
US$ Please choose
US$ Please choose
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概述
产品描述 | Mouse Monoclonal antibody recognizes HIP1R |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | HIP1R |
抗原物种 | Human |
抗原表位 | DRDLQIESLK REVEMLRSEL EKIKLEAQRY IAQLKSQVNA LEGELEEQRK QKQKALVDNE QLRHELAQLR AAQLEGERSQ GLREEAERKA SATEARYNKL KEKHSELVHV HAELLRKNAD TAKQLTVTQQ SQEEVARVKE QLAFQVEQVK RESELKLEEK SDQLEKLKRE LEAKAGELAR AQEALSHTEQ |
偶联标记 | Un-conjugated |
別名 | HIP1R; Huntingtin Interacting Protein 1 Related; HIP12; KIAA0655; ILWEQ; HIP3; Huntingtin-Interacting Protein 1-Related Protein; HIP1-Related Protein; FLJ14000; HIP-12; Huntingtin Interacting Protein 12; Huntingtin-Interacting Protein 12 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O75146 Human Huntingtin-interacting protein 1-related protein |
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基因名称 | HIP1R |
全名 | Huntingtin Interacting Protein 1 Related |
背景介绍 | Enables several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and protein homodimerization activity. Involved in several processes, including positive regulation of signal transduction; protein stabilization; and regulation of organelle organization. Located in clathrin-coated vesicle; cytosol; and ruffle membrane. [provided by Alliance of Genome Resources, Apr 2022] |
生物功能 | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. [Uniprot] |
细胞定位 | Cytoplasm, Cytoplasmic vesicle, Membrane. [Uniprot] |
翻译后修饰 | Acetylation, Phosphoprotein. [Uniprot] |
