anti-Histamine Receptor H1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes Histamine Receptor H1
  • 反应物种: Hu, Rat
  • 预测物种: Ms, Cow, Dog
  • 应用: ICC/IF, IHC-P
  • 特异性: Variants (NP_000852.1; NP_001091681.1; NP_001091682.1; NP_001091683.1) encode the same protein.
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Histamine Receptor H1
  • Brand:
CAT.NO. : ARG63812
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes Histamine Receptor H1
反应物种Hu, Rat
预测物种Ms, Cow, Dog
应用ICC/IF, IHC-P
特异性Variants (NP_000852.1; NP_001091681.1; NP_001091682.1; NP_001091683.1) encode the same protein.
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称Histamine Receptor H1
抗原物种Human
抗原CNENFKKTFKRILH
偶联标记Un-conjugated
別名HRH1, Histamine Receptor H1, Histamine H1 Receptor, HH1R, H1R, Histamine Receptor, Subclass H1, HisH1, H1-R
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay - dependent
IHC-P4 - 6 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 24448 Rat HRH1

GeneID: 3269 Human HRH1

Swiss-port # P31390 Rat Histamine H1 receptor

Swiss-port # P35367 Human Histamine H1 receptor

背景介绍Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
研究领域Immune System antibody; Signaling Transduction antibody
预测分子量56 kDa
翻译后修饰Phosphorylation at sites in the second and third cytoplasmic loops independently contribute to agonist-induced receptor downregulation.
检测图片 (2)
  • ARG63812 anti-Histamine Receptor H1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63812 anti-Histamine Receptor H1 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63812 anti-Histamine Receptor H1 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Colon. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63812 anti-Histamine Receptor H1 antibody at 4 µg/ml dilution followed by HRP-staining.

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