anti-Histamine Receptor H1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG67049
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Histamine Receptor H1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 特异性 | Variants (NP_000852.1; NP_001091681.1; NP_001091682.1; NP_001091683.1) encode the same protein. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Histamine Receptor H1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 150-188 of Human HRH1. |
| 偶联标记 | Un-conjugated |
| 別名 | HRH1, Histamine Receptor H1, Histamine H1 Receptor, HH1R, H1R, Histamine Receptor, Subclass H1, HisH1, H1-R |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 阳性对照 | WB: COLO205 ICC/IF: LoVo cell |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | affinity chromatography |
| 缓冲液 | PBS, 0.02% Sodium azide, 0.5% BSA and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA, 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HRH1 |
| 全名 | Histamine Receptor H1 |
| 背景介绍 | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. [Uniprot] |
| 细胞定位 | Cell membrane, Membrane |
| 预测分子量 | 56 kDa |
| 翻译后修饰 | Phosphorylation at sites in the second and third cytoplasmic loops independently contribute to agonist-induced receptor down-regulation. [Uniprot] |
检测图片 (2)
ARG67049 anti-Histamine Receptor H1 antibody ICC/IF image
ARG67049 anti-Histamine Receptor H1 antibody WB image
Western blot: COLO205 stained with ARG67049 anti-Histamine Receptor H1 antibody at 1:2000 dilution.
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