anti-Histone H1.0 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Histone H1.0
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Histone H1.0
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human Histone H1.0.
  • Brand:
CAT.NO. : ARG41930
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Histone H1.0
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Histone H1.0
抗原物种Human
抗原Synthetic peptide of Human Histone H1.0.
偶联标记Un-conjugated
別名Histone H1.0; H1FV; H10; 0; Histone H1; Histone H1'
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:1000 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Human kidney
实际分子量~ 28 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14958 Mouse H1F0

GeneID: 24437 Rat H1F0

GeneID: 3005 Human H1F0

基因名称H1F0
全名H1 histone family, member 0
背景介绍Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. [provided by RefSeq, Jul 2008]
生物功能Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division. [UniProt]
细胞定位Nucleus. Chromosome. Note=The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes. [UniProt]
预测分子量21 kDa
翻译后修饰Phosphorylated on Ser-17 in RNA edited version.

ADP-ribosylated on Ser-104 in response to DNA damage. [UniProt]
检测图片 (3)
  • ARG41930 anti-Histone H1.0 antibody ICC/IF image

    Immunofluorescence: HepG2 cells stained with ARG41930 anti-Histone H1.0 antibody.

  • ARG41930 anti-Histone H1.0 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis tissue stained with ARG41930 anti-Histone H1.0 antibody.

  • ARG41930 anti-Histone H1.0 antibody WB image

    Western blot: Human kidney lysate stained with ARG41930 anti-Histone H1.0 antibody.

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