anti-HIV protease antibody [1696]
![anti-HIV protease antibody [1696]](/upload/image/products/1696_1_210_205.jpg)
![anti-HIV protease antibody [1696]](/upload/image/products/1696_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
-
Brand:
CAT.NO. : ARG63002
US＄ Please choose
US＄ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [1696] recognizes HIV protease |
|---|---|
| 反应物种 | HIV |
| 应用 | ELISA, FuncSt, WB |
| 特异性 | The clone 1696 recognizes free N-terminus of mature HIV protease (HIV-1 and HIV-2), an enzyme that hydrolyzes polyproteins of HIV viruses into functional proteins. 1696 does not react with the precursor. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1696 |
| 同位型 | IgG1 |
| 靶点名称 | HIV protease |
| 抗原物种 | HIV |
| 抗原 | Bacterially expressed full-length HIV-1 protease |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Functional studies: The clone 1696 strongly inhibits the enzyme activity of HIV-1 and HIV-2 proteases. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from ascites by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | The HIV protease (PR) hydrolyzes polyproteins of HIV virus into functional protein products that are essential for its assembly and subsequent activity. This maturation process occurs as the virion buds from the host cell. HIV protease inhibitors are used in the treatment of patients with AIDS and were considered the first breakthrough in over a decade of AIDS research. HIV protease inhibitors can lower the viral load carried by AIDS patients. |
|---|---|
| 研究领域 | Immune System antibody; Microbiology and Infectious Disease antibody |
检测图片 (1)
ARG63002 anti-HIV protease antibody [1696] Dot Blot image
Dot Blot: 1. Recombinant HIV protease (0.2 µg/ml) 2. Recombinant HIV protease (1.0 µg/ml) 3. Recombinant HIV protease (2.0 µg/ml) stained with ARG63002 anti-HIV protease antibody [1696].
参考文献
克隆号文献
Diversification and specialization of HIV protease function during in vitro evolution.
WB /
Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
New Products
