anti-HIV protease antibody [1696] (azide free)
![anti-HIV protease antibody [1696] (azide free)](/upload/image/products/1696_1_210_205.jpg)
![anti-HIV protease antibody [1696] (azide free)](/upload/image/products/1696_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
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- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG63001
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Product Details
概述
| 产品描述 | Azide free Mouse Monoclonal antibody [1696] recognizes HIV protease |
|---|---|
| 反应物种 | HIV |
| 应用 | ELISA, FuncSt, WB |
| 特异性 | The clone 1696 recognizes free N-terminus of mature HIV protease (HIV-1 and HIV-2), an enzyme that hydrolyzes polyproteins of HIV viruses into functional proteins. 1696 does not react with the precursor. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1696 |
| 同位型 | IgG1 |
| 靶点名称 | HIV protease |
| 抗原物种 | HIV |
| 抗原 | Bacterially expressed full-length HIV-1 protease |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Functional studies: The clone 1696 strongly inhibits the enzyme activity of HIV-1 and HIV-2 proteases. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯化说明 | 0.2 µm filter sterilized. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | The HIV protease (PR) hydrolyzes polyproteins of HIV virus into functional protein products that are essential for its assembly and subsequent activity. This maturation process occurs as the virion buds from the host cell. HIV protease inhibitors are used in the treatment of patients with AIDS and were considered the first breakthrough in over a decade of AIDS research. HIV protease inhibitors can lower the viral load carried by AIDS patients. |
|---|---|
| 研究领域 | Immune System antibody; Microbiology and Infectious Disease antibody |
检测图片 (1)
ARG63001 anti-HIV protease antibody [1696] (azide free) Dot Blot image
Dot Blot: 1. Recombinant HIV protease (0.2 µg/ml) 2. Recombinant HIV protease (1.0 µg/ml) 3. Recombinant HIV protease (2.0 µg/ml) stained with ARG63001 anti-HIV protease antibody [1696] (azide free).
参考文献
克隆号文献
Diversification and specialization of HIV protease function during in vitro evolution.
WB /
Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
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