anti-HLA B7 antibody [BB7.1]

产品描述: Mouse Monoclonal antibody [BB7.1] recognizes HLA B7
反应物种: Hu, NHuPrm
应用: FACS
特异性: The clone BB7.1 recognizes the HLA-B7 antigen. Although highly specific, it can cross-react with HLA-B42 antigen.
宿主: Mouse
克隆: Monoclonal
克隆号: BB7.1
同位型: IgG1
靶点名称: HLA B7

CAT.NO. : ARG65413

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [BB7.1] recognizes HLA B7
反应物种	Hu, NHuPrm
应用	FACS
特异性	The clone BB7.1 recognizes the HLA-B7 antigen. Although highly specific, it can cross-react with HLA-B42 antigen.
宿主	Mouse
克隆	Monoclonal
克隆号	BB7.1
同位型	IgG1
靶点名称	HLA B7
抗原	Papain solubilised HLA-A2, B7
偶联标记	Un-conjugated
別名	SPDA1; HLAB; AS; MHC class I antigen B*7; HLA class I histocompatibility antigen, B-7 alpha chain

应用说明

应用建议

应用	推荐稀释比
FACS	1 - 4 µg/ml

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from cell culture supernatant by protein-A affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3106 Human HLA-B Swiss-port # P01889 Human HLA class I histocompatibility antigen, B-7 alpha chain
基因名称	HLA-B
全名	major histocompatibility complex, class I, B
背景介绍	HLA-B7allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS). The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.
生物功能	Involved in the presentation of foreign antigens to the immune system. [UniProt]
研究领域	Immune System antibody
预测分子量	40 kDa
翻译后修饰	Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).