anti-HLA Class I antibody [MEM-123]

产品描述: Mouse Monoclonal antibody [MEM-123] recognizes HLA Class I
反应物种: Hu, Bov, NHuPrm
应用: ELISA, FACS, IP
特异性: The clone MEM-123 reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
宿主: Mouse
克隆: Monoclonal
克隆号: MEM-123
同位型: IgG3
靶点名称: HLA Class I

CAT.NO. : ARG63005

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [MEM-123] recognizes HLA Class I
反应物种	Hu, Bov, NHuPrm
应用	ELISA, FACS, IP
特异性	The clone MEM-123 reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
宿主	Mouse
克隆	Monoclonal
克隆号	MEM-123
同位型	IgG3
靶点名称	HLA Class I
抗原	COS-7 African green monkey kidney cells
偶联标记	Un-conjugated
別名	MHC class I antigen A*1; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from hybridoma culture supernatant by protein A-affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3105 Human HLA-A Swiss-port # P30443 Human HLA class I histocompatibility antigen, A-1 alpha chain
基因名称	HLA-A
全名	major histocompatibility complex, class I, A
背景介绍	HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteinsexpressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
生物功能	Involved in the presentation of foreign antigens to the immune system. [UniProt]
研究领域	Immune System antibody
预测分子量	40 kDa
翻译后修饰	Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

检测图片 (1)

ARG63005 anti-HLA Class I antibody [MEM-123] FACS image
Flow Cytometry: Human peripheral blood stained with ARG63005 anti-HLA Class I antibody [MEM-123], followed by APC-conjugated Goat anti-Mouse antibody.

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