anti-HLA Class I antibody [MEM-81]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [MEM-81] recognizes HLA Class I
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The clone MEM-81 reacts with human classical MHC Class I molecules in native cell-surface forms. MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: MEM-81
  • 同位型: IgG1
  • 靶点名称: HLA Class I
  • Brand:
CAT.NO. : ARG63004
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Product Details
概述
产品描述Mouse Monoclonal antibody [MEM-81] recognizes HLA Class I
反应物种Hu
应用FACS
特异性The clone MEM-81 reacts with human classical MHC Class I molecules in native cell-surface forms. MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.
宿主Mouse
克隆Monoclonal
克隆号MEM-81
同位型IgG1
靶点名称HLA Class I
抗原Leukocytes of a patient suffering with LGL type leukemia.
偶联标记Un-conjugated
別名MHC class I antigen A*1; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain
应用说明
应用建议
应用推荐稀释比
FACS1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from ascites by protein-A affinity chromatography.
纯度> 95% (by SDS-PAGE)
缓冲液PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂15 mM Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3105 Human HLA-A

Swiss-port # P30443 Human HLA class I histocompatibility antigen, A-1 alpha chain

基因名称HLA-A
全名major histocompatibility complex, class I, A
背景介绍HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteinsexpressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
生物功能Involved in the presentation of foreign antigens to the immune system. [UniProt]
研究领域Immune System antibody
预测分子量40 kDa
翻译后修饰Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
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