anti-HLA G antibody [MEM-G/9] (Biotin)

产品描述: Biotin-conjugated Mouse Monoclonal antibody [MEM-G/9] recognizes HLA G
反应物种: Hu
不反应物种: Ms
应用: FACS
特异性: The clone MEM-G/9 reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. Reactivity with HLA-G3 was also reported. MEM-G/9 is standard reagent thoroughly validated during 3rd International Conference on HLA-G (Paris, 2003).
宿主: Mouse
克隆: Monoclonal
克隆号: MEM-G/9
同位型: IgG1

CAT.NO. : ARG10095

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Size:

50 μg

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Product Details

概述

产品描述	Biotin-conjugated Mouse Monoclonal antibody [MEM-G/9] recognizes HLA G
反应物种	Hu
不反应物种	Ms
应用	FACS
特异性	The clone MEM-G/9 reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. Reactivity with HLA-G3 was also reported. MEM-G/9 is standard reagent thoroughly validated during 3rd International Conference on HLA-G (Paris, 2003).
宿主	Mouse
克隆	Monoclonal
克隆号	MEM-G/9
同位型	IgG1
靶点名称	HLA G
抗原物种	Human
抗原	Recombinant human HLA-G refolded with beta2-microglobulin and peptide.
偶联标记	Biotin
別名	HLA G antigen; MHC class I antigen G; HLA class I histocompatibility antigen, alpha chain G; MHC-G

应用说明

应用建议

应用	推荐稀释比
FACS	1 - 5 µg/ml

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3135 Human HLA-G Swiss-port # P17693 Human HLA class I histocompatibility antigen, alpha chain G
基因名称	HLA-G
全名	major histocompatibility complex, class I, G
背景介绍	HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
生物功能	Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. [UniProt]
研究领域	Immune System antibody
预测分子量	38 kDa

检测图片 (1)

ARG10095 anti-HLA G antibody [MEM-G/9] (Biotin) FACS image
Flow Cytometry: Separation of HLA-G transfected LCL cells (red) from K562 cells (blue). Cells were stained with ARG10095 anti-HLA G antibody [MEM-G/9] (Biotin) at 4 µg/ml dilution, followed by Streptavidin (APC).

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